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mavorixafor will raise the level or result of codeine by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a solid CYP2D6 inhibitor) is contraindicated with medicine which might be highly dependent on CYP2D6 for clearance.Optum Perks is a telehealth provider that connects you with an online health-related Specialist with you